[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"$funNjjO3iD3G_W12HGA1bejJk0ZYahZU8_ZDFvKkRt-U":3},{"sponsor":4,"sponsorVariants":5,"totalTrials":6,"truncated":7,"activeTrials":8,"phase3Count":9,"totalEnrollment":10,"activePrograms":11,"nonDrugCount":12,"topConditions":13,"upcomingReadouts":36,"phaseBuckets":86,"rows":93},"Ain Shams University",[4],1812,false,326,212,176741,196,1019,[14,17,20,22,25,28,31,33],{"name":15,"count":16},"Anesthesia",53,{"name":18,"count":19},"Post Operative Pain",27,{"name":21,"count":19},"Postoperative Pain",{"name":23,"count":24},"Sepsis",19,{"name":26,"count":27},"Periodontitis",14,{"name":29,"count":30},"Breast Cancer",13,{"name":32,"count":30},"Analgesia",{"name":34,"count":35},"Covid19",12,[37,42,47,52,57,62,67,72,77,81],{"nctId":38,"briefTitle":39,"date":40,"intervention":41},"NCT06663995","Evaluation of Locally Delivered Propolis Gels in Periodontitis","2024-06-24","Study Group",{"nctId":43,"briefTitle":44,"date":45,"intervention":46},"NCT06467318","Does Non-Steroidal Anti-inflammatory Drugs Decrease the Quality of Pleurodesis After Mechanical Pleural Abrasion\u002FPleurectomy for Treatment of Pneumothorax?","2024-09","Paracetamol",{"nctId":48,"briefTitle":49,"date":50,"intervention":51},"NCT06568289","Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravidae","2024-09-01","Lignocaine",{"nctId":53,"briefTitle":54,"date":55,"intervention":56},"NCT06486025","Protocols for Magnesium Sulfate Maintenance Dose in Overweight and Obese Women Diagnosed With Preeclampsia","2024-09-15","maintenance magnesium sulphate1g\u002Fh",{"nctId":58,"briefTitle":59,"date":60,"intervention":61},"NCT06485661","Effect of Captopril on GLS in Duchenne Myodystrophy","2024-09-30","Captopril",{"nctId":63,"briefTitle":64,"date":65,"intervention":66},"NCT06427707","The Effect of Adding Either Propofol or Ketamine to Magnesium and Lidocaine Infusions in Nasal Surgeries.","2024-10-31","Intravenous Infusion of propofol, lidocaine, Magnesium sulfate",{"nctId":68,"briefTitle":69,"date":70,"intervention":71},"NCT06698666","Efficacy of Statins Among Major Depressive Disorder","2024-12-04","Rosuvastatin 10 mg tablet.",{"nctId":73,"briefTitle":74,"date":75,"intervention":76},"NCT06621004","Low Dose Magnesium Sulphate","2024-12-31","Patients will receive propranolol 1-2 mg.",{"nctId":78,"briefTitle":79,"date":75,"intervention":80},"NCT06613893","Effect of Inhalational Anesthesia Versus Total Intravenous Anesthesia on Blood Glucose in Type 2 Diabetes Patients","TIVA",{"nctId":82,"briefTitle":83,"date":84,"intervention":85},"NCT06631612","Daily Versus Alternate Day Regimen of Iron Supplementation in Children with Iron Deficiency Anemia","2025-01","ferric hydroxide polymaltose 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Study Between Dexmedetomidine & Neostigmine as an Adjuvant to Local Anesthetic Mixture in Peribulbar Block in Vitreoretinal Surgeries","COMPLETED",[87],"2024-03-30","2023-01-20",81,[109,110],"Vitreoretinal Surgeries","Local Anesthesia",[95,112,113],"Neostigmine","Saline",{"nctId":115,"briefTitle":116,"status":103,"phases":117,"primaryCompletion":118,"completion":119,"start":120,"enrollment":121,"conditions":122,"interventions":124},"NCT04171349","Articaine vs Dexmedetomidine Supplemented Articaine",[87],"2019-10-01","2019-11-01","2019-06-01",50,[123],"Renal Failure",[125,95],"Articaine",{"nctId":127,"briefTitle":128,"status":103,"phases":129,"primaryCompletion":130,"completion":130,"start":131,"enrollment":121,"conditions":132,"interventions":134},"NCT05778305","Effect of Dexmedetomidine on Left Ventricular Function in Coronary Artery Bypass Graft Surgery Outcome",[87],"2023-12-31","2023-01-29",[133],"Effect of Drug in CABAG Patients",[95],0,{"trials":137,"activeCount":186,"soonestReadout":168},[138,151,163,174],{"nctId":139,"briefTitle":140,"status":141,"phases":142,"primaryCompletion":143,"completion":144,"start":145,"enrollment":146,"conditions":147,"interventions":149},"NCT06958367","Effect of Dexmedetomidine on Acute Kidney Injury After Ascending Aortic Surgeries","NOT_YET_RECRUITING",[88],"2026-05-02","2026-05-03","2025-05-01",78,[148],"Aki After Ascending Aortic Surgeries",[95,150],"Normal Saline",{"nctId":152,"briefTitle":153,"status":103,"phases":154,"primaryCompletion":155,"completion":156,"start":157,"enrollment":158,"conditions":159,"interventions":161},"NCT04678050","Dexmedetomidine Compared to Ketofol for Sedation in Paediatrics",[88],"2021-12-10","2021-12-30","2020-10-10",40,[160],"Vital Signs",[162,95],"Ketamine\u002F propofol",{"nctId":164,"briefTitle":165,"status":166,"phases":167,"primaryCompletion":168,"completion":168,"start":145,"enrollment":169,"conditions":170,"interventions":172},"NCT07023991","Dexmedetomidine Added to Bupivacaine for ESP Block in Children Undergoing Lower Abdominal Surgeries","ENROLLING_BY_INVITATION",[88],"2025-08-31",30,[171],"Post-operative Pain",[173,95],"Bupivacaine",{"nctId":175,"briefTitle":176,"status":103,"phases":177,"primaryCompletion":178,"completion":179,"start":180,"enrollment":181,"conditions":182,"interventions":183},"NCT06502262","A Comparative Study of Intrathecal Dexmedetomidine and Fentanyl As Additives to Bupivacaine in Pott's Fracture",[88],"2024-08-15","2024-09-05","2024-01-15",60,[18],[184,185,95],"Bupivacaine Hydrochloride","Fentanyl",2,{"trials":188,"activeCount":186,"soonestReadout":219},[189,202,215,228,238,250],{"nctId":190,"briefTitle":191,"status":103,"phases":192,"primaryCompletion":193,"completion":194,"start":195,"enrollment":196,"conditions":197,"interventions":198},"NCT04892420","Comparison Between Adjuvants Added to Bupivacaine in Adductor Canal Block",[89],"2021-08-20","2021-10-30","2021-06-09",120,[15],[199,95,200,201],"Dexamethasone","Magnesium sulfate","Bupivacain",{"nctId":203,"briefTitle":204,"status":103,"phases":205,"primaryCompletion":206,"completion":207,"start":208,"enrollment":209,"conditions":210,"interventions":213},"NCT05327088","Epidural Dexmedetomidine vs Nalbuphine for Labor Analgesia",[89],"2022-02-12","2022-03-12","2021-09-12",64,[211,212],"Epidural Anesthesia","Labor Pain",[95,214],"Nalbuphine",{"nctId":216,"briefTitle":217,"status":141,"phases":218,"primaryCompletion":219,"completion":219,"start":220,"enrollment":181,"conditions":221,"interventions":225},"NCT07101367","A Comparative Study Between Dexmedetomidine Versus Methylprednisolone on Induced Inflammatory Response in Patients Undergoing On-pump CABG",[88,89],"2026-08-31","2025-09-01",[222,223,224],"Coronary Artery Disease","Systemic Inflammatory Response Syndrome","Postoperative Complications",[226,95,227],"Normal saline","Methylprednisolone",{"nctId":229,"briefTitle":230,"status":231,"phases":232,"primaryCompletion":233,"completion":194,"start":234,"enrollment":121,"conditions":235,"interventions":237},"NCT04926454","Efficacy of Adding Dexmedetomidine as an Adjuvant to Bupivacaine in TAP Block and Caudal Block","UNKNOWN",[88,89],"2021-10-25","2020-09-22",[236],"Pain, Postoperative",[95],{"nctId":239,"briefTitle":240,"status":241,"phases":242,"primaryCompletion":243,"completion":244,"start":245,"enrollment":181,"conditions":246,"interventions":248},"NCT07519863","The Effect of Dormicum-Ketamine Versus Dexmedetomidine on Emergence Delirium During Deep Sedation in Paediatric Burn Patients","RECRUITING",[89],"2026-11","2026-12","2025-11-20",[247],"Emergence Delirium in Pediatric Anesthesia",[249,95],"Midazolam + Ketamine",{"nctId":251,"briefTitle":252,"status":231,"phases":253,"primaryCompletion":254,"completion":254,"start":255,"enrollment":196,"conditions":256,"interventions":258},"NCT04058899","Dexmedetomidine Versus Nalbuphine in Prevention of Emergence Agitation Following Adenotonsillectomy in Pediatrics",[88,89],"2019-09","2019-03-05",[257],"Emergence Delirium",[95,214],{"trials":260,"activeCount":135},[261,274,288,298],{"nctId":262,"briefTitle":263,"status":231,"phases":264,"primaryCompletion":156,"completion":265,"start":266,"enrollment":267,"conditions":268,"interventions":271},"NCT04576975","Ketamine Infusion vs Dexmedetomidine Infusion in Obese Patients Undergoing Bariatric Surgery",[90],"2022-07-01","2021-04-20",90,[269,270],"Morbid Obesity","Surgery",[272,95,273],"Ketamine","Normal Saline 0.9%",{"nctId":275,"briefTitle":276,"status":103,"phases":277,"primaryCompletion":278,"completion":279,"start":280,"enrollment":158,"conditions":281,"interventions":285},"NCT07241351","Dexmedetomidine as an Adjunct to Fentanyl for Term Neonates on Mechanical Ventilation",[89,90],"2024-11-01","2025-07-01","2024-03-01",[32,282,283,284],"Sedation and Analgesia","Neonatal","Mechanical Ventilation in Neonates",[95,286,287],"fentanyl 1mcg\u002Fkg\u002Fhr","fentanyl 0.5 mcg\u002Fkg\u002Fhr",{"nctId":289,"briefTitle":290,"status":103,"phases":291,"primaryCompletion":292,"completion":292,"start":293,"enrollment":181,"conditions":294,"interventions":296},"NCT05671081","Dexmedetomidine Versus Magnesium Sulfate in Ultrasound Guided Bilateral Bi-level Erector Spinae Plane Block in Corrective Scoliosis Surgery",[90],"2024-03-15","2023-01-05",[295],"Anesthesia , Analgesia",[95,200,297],"Narcotic Analgesics",{"nctId":299,"briefTitle":300,"status":103,"phases":301,"primaryCompletion":302,"completion":302,"start":303,"enrollment":304,"conditions":305,"interventions":307},"NCT04704622","Comparison Between Dexmeditomidine, Midazolam and Ketamine as a Sedative to Help Cannula Insertion in Pediatric Patient",[89,90],"2021-02-15","2021-01-01",150,[306],"Cannula Site Pain",[272,308,95],"Midazolam",{"trials":310,"activeCount":425,"soonestReadout":168},[311,321,333,345,354,364,373,384,393,403,412],{"nctId":312,"briefTitle":313,"status":103,"phases":314,"primaryCompletion":315,"completion":315,"start":316,"enrollment":317,"conditions":318,"interventions":319},"NCT05626998","Dexmedetomidine Versus Gabapentin Premedication on the Emergence Agitation After Rhinoplasty",[91],"2023-04-30","2022-11-01",153,[15],[95,320],"Gabapentin",{"nctId":322,"briefTitle":323,"status":103,"phases":324,"primaryCompletion":325,"completion":326,"start":327,"enrollment":328,"conditions":329,"interventions":331},"NCT07475156","The Effect of Dexmedetomidine Infusion Alone Versus the Combination of Dexmedetomidine and Melatonin on Reduction of Post-operative Delirium (POD) After Open Brain Surgeries",[91],"2026-01-15","2026-02-01","2025-08-01",100,[330],"Post Operative Delerium",[95,332],"Melatonin",{"nctId":334,"briefTitle":335,"status":103,"phases":336,"primaryCompletion":337,"completion":338,"start":339,"enrollment":158,"conditions":340,"interventions":343},"NCT04607525","Dexmedetomidine Infusion Effect on Hemodynamic Variables During Craniotomy",[91],"2021-01-20","2021-01-26","2020-11-21",[341,342],"Hemodynamic Instability","Supratentorial Neoplasms",[95,344],"normal saline",{"nctId":346,"briefTitle":347,"status":231,"phases":348,"primaryCompletion":265,"completion":349,"start":350,"enrollment":351,"conditions":352,"interventions":353},"NCT05323565","Dexmedetomine vs Dexamethasone in TAB Block for Abdominal Surgries",[91],"2022-07-05","2022-04-01",45,[15],[95],{"nctId":355,"briefTitle":356,"status":103,"phases":357,"primaryCompletion":358,"completion":359,"start":360,"enrollment":361,"conditions":362,"interventions":363},"NCT03438240","Dexmedetomidine Versus Fentanyl Plus Bupivacaine for Epidural Analgesia With General Anesthesia for Lumbar Disc Operations",[91],"2018-07-05","2018-08-15","2018-02-12",80,[15],[173,185,95],{"nctId":365,"briefTitle":366,"status":231,"phases":367,"primaryCompletion":368,"completion":368,"start":369,"enrollment":370,"conditions":371,"interventions":372},"NCT06181682","Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy",[91],"2024-03","2024-01",70,[15],[95,308],{"nctId":374,"briefTitle":375,"status":241,"phases":376,"primaryCompletion":377,"completion":378,"start":379,"enrollment":370,"conditions":380,"interventions":382},"NCT07154849","Comparative Study Between the Efficacy of Intravenous Hydrocortisone and Intravenous Dexmedetomidine for Prevention of Postoperative Shivering After General Anaesthesia for Abdominal Surgeries",[91],"2025-11-01","2025-12-20","2024-11-11",[381],"Shivering",[383,95],"Hydrocortisone",{"nctId":385,"briefTitle":386,"status":103,"phases":387,"primaryCompletion":388,"completion":388,"start":292,"enrollment":361,"conditions":389,"interventions":391},"NCT06312618","Propofol Versus Dexmedetomidine Effect on Prevention Emergence Agitation",[91],"2025-03-15",[390],"Emergence Agitation",[392,95],"Propofol",{"nctId":394,"briefTitle":395,"status":231,"phases":396,"primaryCompletion":397,"completion":398,"start":399,"enrollment":400,"conditions":401,"interventions":402},"NCT03393988","Techniques for Perioperative Analgesia for Live Liver Donors; A Pilot Study",[91],"2018-12","2019-02","2017-12-07",20,[15],[185,95],{"nctId":404,"briefTitle":405,"status":166,"phases":406,"primaryCompletion":168,"completion":168,"start":407,"enrollment":181,"conditions":408,"interventions":410},"NCT07034898","Dexmedetomidine vs Labetalol for Airway Stress in Hypertensive Craniotomy Patients",[91],"2025-04-01",[409],"Airway Stress Response",[95,411],"Labetalol",{"nctId":413,"briefTitle":414,"status":415,"phases":416,"primaryCompletion":417,"completion":418,"start":419,"enrollment":420,"conditions":421,"interventions":423},"NCT07513935","Comparison of Combined Dexmedetomidine and Ketamine (Ketodex) Versus Dexmedetomidine Alone in Awake Mapping for Deep Brain Stimulation: A Randomized Controlled Trial","ACTIVE_NOT_RECRUITING",[91],"2026-09-03","2026-09-30","2026-03-03",24,[422],"Intraoperative Awareness",[424,95],"Ketodex",3,{"trials":427,"activeCount":563,"soonestReadout":327},[428,439,448,457,468,479,491,502,514,524,533,543,553],{"nctId":429,"briefTitle":430,"status":231,"phases":431,"primaryCompletion":432,"completion":433,"start":434,"enrollment":370,"conditions":435,"interventions":437},"NCT05361642","Regional Nasal Block and Dexmedetomidine in Endoscopic Sinus Surgery",[92],"2022-11-05","2022-12-05","2022-02-03",[436],"Drug Use",[438,95],"Bupivacaine HCl 0.5% 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