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of Intravenous Dexmedetomidine Versus Dexamethasone for Management of Repound Pain After Supraclavicular Brachial Plexus Block","UNKNOWN",[90],"2025-03","2024-05",111,[114],"Trauma Injury",[97],{"nctId":117,"briefTitle":118,"status":119,"phases":120,"primaryCompletion":121,"completion":122,"start":123,"enrollment":124,"conditions":125,"interventions":127},"NCT07279727","Ultrasound-Guided Infraclvicular Block Using Dexmedetomidine Versus Nalbuphine as Adjuvants to Bupivacaine in Upper Limb Orthopedic Surgery","NOT_YET_RECRUITING",[90],"2026-12-31","2027-04-01","2026-01-01",66,[126],"Regional Anaesthesia",[128,97],"Nalbuphine",{"nctId":130,"briefTitle":131,"status":119,"phases":132,"primaryCompletion":133,"completion":133,"start":134,"enrollment":135,"conditions":136,"interventions":138},"NCT06668220","Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics",[90],"2026-10-30","2024-11-20",50,[137],"Caudal Block for Postoperative Analgesia",[97,139],"Bupivacain",2,{"trials":142,"activeCount":102},[143,155,166,178,190,201,210,220,234,242],{"nctId":144,"briefTitle":145,"status":146,"phases":147,"primaryCompletion":148,"completion":148,"start":149,"enrollment":150,"conditions":151,"interventions":152},"NCT02818985","Analgesia in Knee Arthroscopic Surgery","COMPLETED",[91],"2017-02","2016-06",60,[15],[153,97,154],"Dexamethasone","Saline",{"nctId":156,"briefTitle":157,"status":146,"phases":158,"primaryCompletion":159,"completion":159,"start":160,"enrollment":161,"conditions":162,"interventions":164},"NCT02382432","Dexmedetomidine in Post Spinal Anesthesia Shivering",[91],"2014-12","2013-12",120,[163],"Shivering Caused by Spinal Anesthesia",[165,97],"Pethidine 0.4mg\u002Fkg",{"nctId":167,"briefTitle":168,"status":146,"phases":169,"primaryCompletion":170,"completion":170,"start":171,"enrollment":172,"conditions":173,"interventions":175},"NCT02820610","Intraperitoneal Analgesia in Pediatric Laparoscopy",[91],"2019-09","2016-08",97,[174],"Analgesia",[97,176,177],"Magnesium Sulfate","Normal saline 0.9 %",{"nctId":179,"briefTitle":180,"status":146,"phases":181,"primaryCompletion":182,"completion":182,"start":183,"enrollment":184,"conditions":185,"interventions":187},"NCT03412474","Suprazygomatic Block in Cleft Palate Surgery in Children",[91],"2018-08-31","2018-01-14",80,[186],"Cleft Palate",[188,97,189],"Bupivacaine","paracetamol",{"nctId":191,"briefTitle":192,"status":146,"phases":193,"primaryCompletion":194,"completion":194,"start":195,"enrollment":196,"conditions":197,"interventions":199},"NCT02727621","Dexmedetomidine Sedation and Cardiopulmonary Bypass",[91],"2016-09","2016-04",100,[198],"Coronary Artery Bypass Grafting",[97,200],"propofol",{"nctId":202,"briefTitle":203,"status":146,"phases":204,"primaryCompletion":205,"completion":206,"start":171,"enrollment":150,"conditions":207,"interventions":209},"NCT02886429","Post- Thoracotomy Paravertebral Block",[91],"2018-08","2018-10",[208],"Pain, Postoperative",[188,97],{"nctId":211,"briefTitle":212,"status":108,"phases":213,"primaryCompletion":206,"completion":214,"start":215,"enrollment":150,"conditions":216,"interventions":218},"NCT03163238","Dexmedetomidine and the Inflammatory Response in Pediatric Cardiac Surgery",[91],"2018-12","2017-05-30",[217],"Cardiac Surgical Procedures",[97,219],"Normal saline",{"nctId":221,"briefTitle":222,"status":108,"phases":223,"primaryCompletion":224,"completion":225,"start":226,"enrollment":227,"conditions":228,"interventions":231},"NCT02935933","Paravertebral Morphine Versus Dexmedetomidine on Acute and Chronic Postmastectomy Pain",[90,91],"2017-09","2018-06","2016-10",90,[229,230],"Acute Pain","Chronic Pain",[232,233,97],"bupivicaine","morphine",{"nctId":235,"briefTitle":236,"status":146,"phases":237,"primaryCompletion":182,"completion":182,"start":238,"enrollment":184,"conditions":239,"interventions":241},"NCT03156296","Transversus Abdominis Plane Block Using Dexmedetomidine and Bupivacaine",[91],"2017-06-10",[240],"Laparoscopic Orcheopexy",[97,188],{"nctId":243,"briefTitle":244,"status":108,"phases":245,"primaryCompletion":246,"completion":247,"start":248,"enrollment":249,"conditions":250,"interventions":252},"NCT03024957","Effect of Intrathecal Morphine, Dexmedetomidine or Both in Combination to Bupivacaine on Immunity",[90,91],"2018-09","2021-02","2017-01",30,[251],"Immune System Suppression",[253,97,188],"Morphine Sulfate",{"trials":255,"activeCount":529,"soonestReadout":514},[256,268,280,290,301,311,321,331,341,350,358,369,378,391,401,413,421,431,442,451,463,470,481,493,502,510,518],{"nctId":257,"briefTitle":258,"status":119,"phases":259,"primaryCompletion":260,"completion":261,"start":262,"enrollment":263,"conditions":264,"interventions":266},"NCT07326397","Comparison Between Intrathecal Magnesium Sulphate & Dexmedetomidine in DHS",[92],"2027-11-01","2027-12-01","2026-02-01",92,[265],"Effects of Dexmedetomidine & Magnesium Sulphate on Patients Undergoing DHS",[97,267],"Magnesium Sulphate",{"nctId":269,"briefTitle":270,"status":119,"phases":271,"primaryCompletion":272,"completion":273,"start":274,"enrollment":275,"conditions":276,"interventions":278},"NCT06799442","Dexmedetomidine Versus Fentanyl as Adjuvants to Erector Spinae Plane Block for Postoperative Analgesia Following Simple Nephrectomy: A Randomized Clinical Trial",[91,92],"2025-12-01","2026-03-01","2025-03-01",46,[277],"Nephrectomy",[97,279],"fentanyl",{"nctId":281,"briefTitle":282,"status":146,"phases":283,"primaryCompletion":284,"completion":285,"start":149,"enrollment":227,"conditions":286,"interventions":288},"NCT02927379","Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress",[92],"2016-12","2017-10",[287],"Abdominal Cancer",[97,289,188],"Ketamine",{"nctId":291,"briefTitle":292,"status":146,"phases":293,"primaryCompletion":294,"completion":295,"start":296,"enrollment":297,"conditions":298,"interventions":299},"NCT03328299","Pharmacokinetics and Dynamics of Dexmedetomidine as Adjuvant in TAP Block",[91,92],"2018-12-01","2019-09-01","2017-11-11",24,[15],[97,300],"bupivacaine",{"nctId":302,"briefTitle":303,"status":108,"phases":304,"primaryCompletion":305,"completion":82,"start":306,"enrollment":227,"conditions":307,"interventions":309},"NCT06082076","Prevention of Shivering Associated With Spinal Anesthesia",[91,92],"2024-11","2023-11",[308],"Shivering, Spinal Anesthesia",[97,289,310],"Meperidine",{"nctId":312,"briefTitle":313,"status":146,"phases":314,"primaryCompletion":206,"completion":315,"start":316,"enrollment":227,"conditions":317,"interventions":319},"NCT02720705","Transbucal Dexmedetomidine for Prevention of Sevoflurane Emergence Agitation in Pre-school Children",[91,92],"2018-11","2016-05",[318],"Agitation",[97,320],"saline",{"nctId":322,"briefTitle":323,"status":146,"phases":324,"primaryCompletion":325,"completion":326,"start":327,"enrollment":227,"conditions":328,"interventions":330},"NCT04941508","Mother's Recorded Voice Versus Dexmedetomidine on Postoperative Agitation",[92],"2021-11-03","2021-11-05","2021-06-25",[329],"Agitation, Emergence",[97],{"nctId":332,"briefTitle":333,"status":146,"phases":334,"primaryCompletion":335,"completion":335,"start":238,"enrollment":227,"conditions":336,"interventions":338},"NCT03155646","Dexmedetomidine Versus Clonidine in TAP Block",[91,92],"2019-08-01",[337],"Transversus Abdominis Plane Block",[97,339,340],"Clonidine","Levobupivacaine",{"nctId":342,"briefTitle":343,"status":119,"phases":344,"primaryCompletion":345,"completion":346,"start":274,"enrollment":196,"conditions":347,"interventions":349},"NCT06838650","Beneficial Effects of Low-Dose Intravenous Dexmedetomidine Premedication in Patient Undergoing Laparoscopic Cholecystectomy Under General Anesthesia",[92],"2026-05-01","2026-06-01",[348],"Laparoscopic Cholecystectomy Surgery",[97,154],{"nctId":351,"briefTitle":352,"status":119,"phases":353,"primaryCompletion":273,"completion":354,"start":274,"enrollment":184,"conditions":355,"interventions":357},"NCT06789393","Comparison of the Efficacy of Bupivacaine with and Without Dexmedetomidine As an Adjuvant on Penile Block for Postoperative Pain Relief in Pediatrics Undergoing Hypospadias Repair Surgery",[92],"2027-05-01",[356],"Hypospadias Repair Surgery",[97,188],{"nctId":359,"briefTitle":360,"status":119,"phases":361,"primaryCompletion":345,"completion":362,"start":363,"enrollment":364,"conditions":365,"interventions":367},"NCT06865469","Comparing Efficacy of Intravenous Dexmedetomidine and Lidocaine on Postoperative Analgesia in Patients Undergoing Fracture Hip Surgery",[92],"2026-09-01","2025-05-01",56,[366],"Fracture Hip Surgery",[97,368],"Lidocaine Hydrochloride 2%",{"nctId":370,"briefTitle":371,"status":146,"phases":372,"primaryCompletion":149,"completion":149,"start":373,"enrollment":150,"conditions":374,"interventions":376},"NCT02606409","Dexmedetomidine Versus Propofol for Prolonged Sedation in Poly Traumatized Mechanically Ventilated Patients",[91,92],"2015-11",[375],"Trauma",[97,377],"Propofol",{"nctId":379,"briefTitle":380,"status":146,"phases":381,"primaryCompletion":382,"completion":383,"start":384,"enrollment":227,"conditions":385,"interventions":388},"NCT03060070","Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block",[91,92],"2017-06-25","2017-07-01","2017-03-10",[386,387],"Postoperative Analgesia","Lower Abdominal Cancer",[289,389,390],"dexmedetomidine","control group",{"nctId":392,"briefTitle":393,"status":146,"phases":394,"primaryCompletion":395,"completion":396,"start":397,"enrollment":249,"conditions":398,"interventions":400},"NCT03391609","Peri-operative Dexmedetomidine Infusion in Pre-eclamptic Patients",[91,92],"2018-11-01","2019-01-01","2017-06-18",[399],"Pre-Eclampsia",[97],{"nctId":402,"briefTitle":403,"status":108,"phases":404,"primaryCompletion":405,"completion":406,"start":407,"enrollment":227,"conditions":408,"interventions":411},"NCT02455609","Intrathecal Ketamine, Dexmedetomidine and Both With Bupivacaine for Postoperative Abdominal Cancer Surgery Pain",[91,92],"2015-08","2015-09","2015-03",[409,410],"Therapy","Pain Management",[97,412,188],"ketamine",{"nctId":414,"briefTitle":415,"status":108,"phases":416,"primaryCompletion":417,"completion":306,"start":418,"enrollment":150,"conditions":419,"interventions":420},"NCT05194904","Intravenous Dexmedetomidin on Postoperative Pain After Hypospadias Repair in Children",[91,92],"2023-07","2022-01",[15],[97],{"nctId":422,"briefTitle":423,"status":108,"phases":424,"primaryCompletion":425,"completion":425,"start":426,"enrollment":427,"conditions":428,"interventions":430},"NCT03067896","Dexmedetomidine Versus Magnesium Sulphate 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Block",[93],"2024-02-25",[627,628,97],"Erector Spinae Block","Lumbar Fusion Surgeries",[97,139,219],{"nctId":631,"briefTitle":632,"status":119,"phases":633,"primaryCompletion":634,"completion":635,"start":636,"enrollment":135,"conditions":637,"interventions":638},"NCT07425444","Attenuate the Stress Response in Laparoscopic Cholecystectomy",[93],"2027-02","2027-04","2026-02",[348],[97,639],"Fentanyl- midazolam",{"nctId":641,"briefTitle":642,"status":119,"phases":643,"primaryCompletion":485,"completion":486,"start":487,"enrollment":644,"conditions":645,"interventions":647},"NCT07214701","Sedative and Analgesic Effects of Dexmedetomidine Versus Ketamine in Patients Undergoing Varicocelectomy Under Spinal Anaesthesia: A Prospective Randomized Comparative Trial",[93],58,[646],"Varicocelectomy",[289,97],{"nctId":649,"briefTitle":650,"status":119,"phases":651,"primaryCompletion":272,"completion":123,"start":652,"enrollment":653,"conditions":654,"interventions":656},"NCT06690021","Comparing 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Lower Limb Orthopedic Surgery Under Spinal Anesthesia",[93],"2026-01",[673],"Lower Limb Orthopedic Surgery",[97,541],{"nctId":676,"briefTitle":677,"status":119,"phases":678,"primaryCompletion":485,"completion":486,"start":487,"enrollment":679,"conditions":680,"interventions":682},"NCT07214714","Hemodynamic and Cardiac Effects of Dexmedetomidine Versus Fentanyl by Intravenous Infusion as Adjuncts to General Anesthesia in Patients Undergoing Major Abdominal Cancer Surgeries.",[93],70,[681],"Abdominal Cancer Surgeries",[683,97],"Fentanyl",10,{"trials":686,"activeCount":847,"soonestReadout":548},[687,696,705,714,725,733,743,753,764,773,784,793,802,813,824,836],{"nctId":688,"briefTitle":689,"status":146,"phases":690,"primaryCompletion":691,"completion":692,"start":383,"enrollment":150,"conditions":693,"interventions":695},"NCT03172065","Dexmedetomidine and Laparoscopic Surgery",[94],"2018-07-05","2018-07-09",[694],"Anesthesia 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of Shivering in Women Undergoing Cesarean Section Under Spinal Anaesthesia",[94],"2025-07-01","2025-09-01","2024-02-10",200,[833],"Prevention of Shivering With Spinal Anaesthesia",[835,97],"Ephedrine",{"nctId":837,"briefTitle":838,"status":146,"phases":839,"primaryCompletion":840,"completion":841,"start":842,"enrollment":227,"conditions":843,"interventions":846},"NCT04838379","Ultrasound Guided Rectus Sheath Block and Transversus Abdominis Plane 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Dexamethasone",[93],"2021-09-30","2022-04-20","2020-09-30",99,[15],[153,153],{"nctId":1501,"briefTitle":1502,"status":108,"phases":1503,"primaryCompletion":1027,"completion":1504,"start":1505,"enrollment":196,"conditions":1506,"interventions":1508},"NCT04103684","Steroids in Treatment of Viral Encephalitis",[93],"2021-08-30","2020-03-30",[1507],"Encephalitis, Viral",[1453,153],{"nctId":1510,"briefTitle":1511,"status":108,"phases":1512,"primaryCompletion":1513,"completion":1513,"start":1514,"enrollment":227,"conditions":1515,"interventions":1517},"NCT05549895","Effect of Intrathecal Dexamethasone on Intra-operative Hemodynamic in Elderly Patients Undergoing Urologic Endoscopic Surgery",[93],"2022-10","2022-09",[153,1516],"Urologic Endoscopic Surgery",[153,1180],{"nctId":1519,"briefTitle":1520,"status":108,"phases":1521,"primaryCompletion":1294,"completion":1294,"start":1208,"enrollment":1522,"conditions":1523,"interventions":1524},"NCT05496764","Local Injection of Steroid VS.Glucose 5% 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